https://www.cosmosscholars.com/phms/index.php/jtpr <p><strong>Journal of Translational Proteomics Research </strong>is a scientific journal providing a scholarly forum for novel scientific research in the field of translational proteomics. It covers all areas of human proteomics using multi-disciplinary approaches to untangle complex disease processes .Proteins are fundamental parts of living organisms, as they are the main components of the physiological metabolic pathways of cells. The cause of most human disease lies in the functional dysregulation of protein interactions. Proteomics, which includes the study of cellular protein interactions, has evolved from advances in scientific knowledge and technology.</p> Cosmos Schoalrs Publishing House en-US Journal of Translational Proteomics Research <h4>Policy for Journals/Articles with Open Access</h4>Authors who publish with this journal agree to the following terms:<br /><ol type="a"><ol type="a"><li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a <a href="http://creativecommons.org/licenses/by/3.0/" target="_new">Creative Commons Attribution License</a> that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li></ol></ol><br /><ol type="a"><li>Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work</li></ol><h4>Policy for Journals / Manuscript with Paid Access</h4>Authors who publish with this journal agree to the following terms:<br /><ol type="a"><ol type="a"><li>Publisher retain copyright .</li></ol></ol><br /><ol type="a"><li>Authors are permitted and encouraged to post links to their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work .</li></ol> https://www.cosmosscholars.com/phms/index.php/jtpr/article/view/757 <p class="04-abstract">The mini review is focused on the analysis of published data and the results obtained by author with co-workers about biological activity of anti-DNA (“cationic”) and anti-histone Н1 (“anionic”) auto-antibodies linked with autoimmunity and oncology. The feathures of anti-DNA and-anti histone auto- antibodies, which might be engaged in regulation of tumor cell progressing, are considered.</p> Yuriy Kit Copyright (c) 2017-06-21 2017-06-21 3 1 5 https://www.cosmosscholars.com/phms/index.php/jtpr/article/view/763 Combination of existing antibiotics have been introduced to increase the efficacy for a long time. Synergistic combinations of antibiotics are most desirable due to reduction of doses, toxicity and side effects of the individual antibiotic as well as prolonging in evolution of antibiotic resistance. Recently, antimicrobial peptides (AMPs) are gaining attention as viable alternatives to antibiotics due to the broad spectrum of activities and abundantly present in multicellular organisms that act against invading microbes. The combination of AMPs and conventional antibiotics enables to reduce the overall cost and widen the power of synergistic effects. Synergistic combinations are also reported among AMPs. Despite enormous advantages of synergistic combinations and several reports and uses in clinical medicine, only few underlying mechanisms are revealed. In this review, we overviewed the mechanisms of antimicrobial agents’ synergistic combinations and introduced the proteome chip approach for predicting new synergistic combinations and deciphering the synergy mechanisms. Chien-Sheng Chen Pramod Shah Copyright (c) 2017-07-07 2017-07-07 3 6 11