Global Journal of Hematology and Blood Transfusion  (Volume 6 Issue 1)
A Case of Plasmablastic Lymphoma in an Immunocompetent Individual  Global Journal of Hematology and Blood Transfusion
Pages 6-9

P. Satya Dattatreya and Rekha Bansal

Published: February  2019

Introduction: Plasmablastic Lymphoma, a subtype of Diffuse large B-cell lymphoma is known to occur in association with HIV infection. We report a case of extraoral plasmablastic lymphoma at an unusual site.

Case presentation: 66 years old male patient was evaluated in view of persistent headache and proptosis. He was found to have a frontal mass lesion extending into the orbit. Pathology and IHC confirmed it to be Plasmablastic Lymphoma. He received treatment with DA-R-EPOCH with bortezomib to which he responded extremely well and remains disease free for more than 12 months.

Conclusion: Despite being an aggressive lymphoma with poor prognosis, our patient responded extremely well to the treatment. 

Plasmablastic lymphoma, Immunocompetent, Extraoral disease, Non-Hodgkin’s lymphomas, B-cell lymphoma.