Carbon Dots -A Turn-On Probe for Neurological Disorder

Authors

  • Payel Mukherjee M.R. College of Pharmaceutical Sciences and Research, Bira, Balisha, North 24 Parganas, West Bengal – 743234
  • Manas Chakraborty Calcutta Institute of Pharmaceutical Technology and AHS, Banitabla, Uluberia, Howrah, West Bengal- 711316
  • Goutam Mukhopadhyay BCDA College of Pharmacy and Technology, Campus 2, Hridaypur, Kolkata, West Bengal 700129

DOI:

https://doi.org/10.15379/ijmst.v10i1.2982

Keywords:

Neurological Illnesses, Neuro Drug Delivery Systems, Carbon Dot, Biosensing, Bioimaging, Brain Tumour, Blood-Brain Barrier.

Abstract

The creation of novel methods is essential for the early diagnosis and treatment of neurological illnesses (NDs). The blood-brain barrier (BBB), which can prevent substances from accessing the central nervous system, is the most difficult obstacle to overcome in the development of neural medication delivery systems (CNS). For several biological applications, carbon dots (CDs) have emerged as highly outstanding and promising agents, including the treatment of brain tumours, ND, and bioimaging research. Because of their great qualities, they have a lot of potential for a range of scientific disciplines due to their biocompatibility, tiny size, tunable optical properties, photostability, and straightforward fabrication processes. This article's goal is to provide a summary of current CD research and to make recommendations for future work on creating neural drug delivery systems that can penetrate the BBB and reach the central nervous system. The two main subjects of this review are CD toxicity and unique optical properties. For a variety of neurological illnesses, a unique CD-based drug delivery system is designed in detail. This study also explores the possible applications of CDs for neurodegenerative disease therapies and imaging of brain tumours. The final section provides a summary of present CD sensing applications and projected future developments.

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Published

2023-11-01

How to Cite

[1]
P. . Mukherjee, M. . Chakraborty, and G. . Mukhopadhyay, “Carbon Dots -A Turn-On Probe for Neurological Disorder”, ijmst, vol. 10, no. 1, pp. 1526-1539, Nov. 2023.