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Global Journal of Hematology and Blood Transfusion is committed to dissemination of high-quality research related to the latest trends and advances in the field of Hematology and Blood Transfusion.Read More
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International Journal of Nuclear Medicine Research provides an authoritative setting for the publication of high quality internationally-relevant research with respect to the field of Nuclear Medicine. Nuclear Medicine is crucial to early diagnosis and treatment of diseases that threaten human lives.
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International journal of Gynecology, Obstetrics and Neonatal Care is a peer reviewed medical journal provides up-to-date results of basic and clinical studies in Gynecology, Obstetrics and Neonatology. The primary mission of the journal is to promote improvement in the health.
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International Journal of Advanced Applied Physics Research is a refereed and highly professional journal that publishes premium theoretical and pragmatic papers in the field of Applied Physics.
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International Journal of Cardiology and Lipidology Research is a peer reviewed medical journal which strengthen the research and educational base of Cardiology and Lipidology.We publish original research articles, reviews, case studies, conference papers and short notes related to aforementioned field.
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Journal of Advanced Neuroscience Research is a peer reviewed scientific journal providing fascinating and unique forum for publishing original experimental and review articles.Read More
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World Journal of Oncology Research is a peer-reviewed scientific journal which strengthens the research and educational base of Oncology.Read More
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Journal of Clinical Medicine Research Updates is an international peer reviewed journal related to latest advances in all areas of clinical medicine.Read More
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International Journal of Food Processing Technology is a peer reviewed scientific journal providing an authoritative setting for the publication of internationally-relevant research.Read More
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Journal of Translational Proteomics Research is a scientific journal providing a scholarly forum for novel scientific research in the field of translational proteomics.Read More
Abstract: Alum: Role in Dentistry as a Potent Anti-Plaque and Anti-Caries Agent
| International Journal of Pharmaceuticals and Nutritional Sciences (Volume 3) | |
| Alum: Role in Dentistry as a Potent Anti-Plaque and Anti-Caries Agent |  |
| Pages 6-8 Muhammad Farhanullah Khan and Mahwish Ahmed Karim
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| Abstract | |
| Alum is a cheaper chemical easily available near your home everywhere in the world. It is an ionic compound that is a salt and is a crystalline chemical that has a chemical formula Al . 2 H2 O4 S . 12 H2 O . K. Aluminum has a wide use in the field of dentistry. Its use ranged from its clinical efficay to its pharmaceutical use in the preparation of dental materials and appliances. Pakistan is blessed with the best herbal remedies and alternative practitioners. In Hikmat system of medicine, widely practiced in Pakistan, the alum is used in making manjans (tooth powder), surmeys (eye preparations) and for treating leucorrhea. Alum has been used as ananticaries agent in Hikmat Like wise, other Aluminum salts having Aluminum ion (Al3+) have variety of uses in medical sciences. Aluminum oxide is used as acne face wash as abrasive. | |
| Keywords | |
| Alum, Cheaper, Hikmat, Anti-caries agent, Aluminum ion (Al3+). | |
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Abstract: Sanguinaria Canadensis: Sanguinarine Containing Potent Medicinal Roots and Rhizomes of Broad Antimicrobial and Anti-Inflammatory Activities
| International Journal of Pharmaceuticals and Nutritional Sciences (Volume 3) | |
| Sanguinaria Canadensis: Sanguinarine Containing Potent Medicinal Roots and Rhizomes of Broad Antimicrobial and Anti-Inflammatory Activities | |
| Pages 1-5 Amtul Sami and Mahwish Ahmed Karim Published: 29 July 2019 |
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| Abstract | |
| Sanguinaria canadensis, is a western medicinal roots and rhizomes. The plant is widely distributed in Canada and United states. Sanguinarine, a quartenary ammonium major alkaloid of Sanguinaria, has broad antimicrobial as well as anti-inflammatory properties. Its dried roots and rhizomes are popular for its emetic and expectorant properties and remarkably used as antimicrobial agent. Sanguinarine is widely used commercially in toothpastes and mouthwashes as an antiplaque agent. Crude methanolic extract of red root showed antithrombin, antimicrobial and antimycobacterial activities and its potent activity against Mycobacterium aurum, with MIC values of 62.5 µg/mL proved it a valuable anti-tubercular drug. Chelerythrine chloride was the most active among all with IC50 value of 14.3 µg/mL against M. bovis BCG. Inhibition of Collagenase and bone resorption has been documented, invitro. Sanguinaria canadensis exract and Sanguinaria alkaloids were also tested against H. pylori with significant activity. Its burning capability is used in Homeopathic system of medicine and is indicated there in the ailments of respiratory tract. Sanguinarine has a use in reducing dental plaque and gingivitis and this use is accepted by FDA. In low doses the use of these alkaloids is safe and therapeutic but they are toxic at higher doses. | |
| Keywords | |
| S. canadensis, Sanguinarine, Chelerythrine chloride, Antimicrobial, Anti-inflammatory, Anti-tubercular drug,Mycobacterium aurum, H. pylori, Homeopathy. | |
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Abstract: Evaluation of Asymmetric Dimethylarginine in Diabetic Rats Treated with Flaxseed Oil
| International Journal of Pharmaceuticals and Nutritional Sciences (Volume 1 Issue 1) | |
| Evaluation of Asymmetric Dimethylarginine in Diabetic Rats Treated with Flaxseed Oil | |
| Pages 1-5 Jihan Hussein, Yasmin Abdel Latif, Dalia Medhat, Mona El-Bana and Zakaria El-Khayat Published: 27 December 2017 |
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| Abstract | |
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Objective: The present study aimed to investigate how far supplementation of dietary omega-3 fatty acids could affect endothelial dysfunction and augment elevation of Asymmetric Dimethylarginine (ADMA) in experimental diabetes. Methods: To fulfill our objective, forty male albino rats were divided into four experimental groups as follow: Control, flaxseed oil, diabetic, and treated flaxseed oil groups. After blood sample collection from all groups, plasma was used for estimation of different biochemical parameters including blood glucose and plasma insulin. The levels of liver malondialdehyde (MDA), liver superoxide dismutase (SOD) and plasma nitric oxide (NO) were determined by colorimetric methods. ADMA was estimated by HPLC using fluorescence detector. Results: Streptozotocin (STZ) induced experimental diabetes was shown by the significant elevation in blood glucose levels, insulin resistance and oxidative stress as revealed by a significant increase in the levels of liver MDA accompanied with a significant reduction in SOD activity. In addition, STZ administration significantly elevated ADMA level. In contrast, flaxseed oil supplementation was capable of ameliorating these negative changes in STZ injected rats. Conclusion: Dietary omega-3 fatty acids present in flaxseed oil can ameliorate endothelial dysfunction and elevation of ADMA in STZ induced diabetes. These results could be assigned to the potential antioxidant, anti-apoptotic, and anti-inflammatory effects of flaxseed oil. |
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| Keywords | |
| Diabetes mellitus, ADMA, Endothelial dysfunction, HPLC, Flaxseed oil. | |
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